Uvalde Driver License Office 2901 E. Main St.Uvalde Texas 78801 TX Uvalde 2901 E. Main St.Directions (830) 278-5639 Monday 08:00 am - 05:00 pm Tuesday 08:00 am - 05:00 pm Wednesday 08:00 am - 05:00 pm Thursday 08:00 am - 05:00 pm Friday 08:00 am - 05:00 pm Saturday Closed Sunday Closed