Lowndes County Tax Collector (Vehicle Registration & Title) 1121 Main St.Columbus Mississippi 39701 MS USA 1121 Main St.Directions (662) 329-5700 Monday 08:00 am - 05:00 pm Tuesday 08:00 am - 05:00 pm Wednesday 08:00 am - 05:00 pm Thursday 08:00 am - 05:00 pm Friday 08:00 am - 05:00 pm Saturday Closed Sunday Closed