Driver License & Vehicle Registration Office 202 S. Third St., Suite 113Louisiana Missouri 63353 MO USA 202 S. Third St., Suite 113Directions (573) 754-6864 Monday 08:00 am - 04:30 pm Tuesday 08:00 am - 04:30 pm Wednesday 08:00 am - 04:30 pm Thursday 08:00 am - 04:30 pm Friday 08:00 am - 04:30 pm Saturday Closed Sunday Closed