Driver License & Vehicle Registration Office 303 N. Missouri St.Potosi Missouri 63664 MO USA 303 N. Missouri St.Directions (573) 438-2278 Monday 08:30 am - 05:00 pm Tuesday 08:30 am - 05:00 pm Wednesday 08:30 am - 05:00 pm Thursday 08:30 am - 05:00 pm Friday 08:30 am - 05:00 pm Saturday Closed Sunday Closed